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. 2009 Dec 18;298(3):H736–H745. doi: 10.1152/ajpheart.00935.2009

Fig. 2.

Fig. 2.

Ligation of receptor for advanced glycation end products (RAGE) in HVSMCs increases THP-1 cell binding. A: HVSMCs were incubated with S100B (40 mg/l) from 1 h to 7 days before monocyte-HVSMC binding assays were performed. Values are means ± SE (n = 6). *P < 0.05; **P < 0.001 vs. control. B: HVSMCs were incubated with increasing concentrations of S100B for 3 days before monocyte binding assays. Values are means ± SE (n = 6). *P < 0.05; **P < 0.001 vs. control. C: HVSMCs were incubated for 3 days with S100B (40 mg/l) in the presence of RAGE blocking antibody (10 mg/l) or control IgG. Values are means ± SE (n = 6). *P < 0.001 vs. control; #P < 0.001 vs. S100B in untreated (none) or IgG-treated cells.