. 2009 Dec 30;298(3):F771–F778. doi: 10.1152/ajprenal.00266.2009

Table 1.

Parameters of bladder activity in transvesical CMGs after serial administration of vehicle, 8-OH-DPAT, and WAY-100635 in urethane-anesthetized rats

	VT, ml	CA, cmH₂O	CD, min	RV, ml	VE, %
Vehicle (n = 18)	0.73 ± 0.14	32.92 ± 6.38	0.40 ± 0.10	0.17 ± 0.05	71.6 ± 12.9
Agonist (8-OH-DPAT; 0.3 mg/kg)	0.52 ± 0.13^*	26.66 ± 4.89^*	0.47 ± 0.11	0.06 ± 0.03	86.1 ± 10.6
Antagonist (WAY-100635; 0.1 mg/kg)	1.55 ± 0.36^*^†	36.74 ± 6.47^†	0.36 ± 0.10^†	1.05 ± 0.31^*^†	29.3 ± 22.9^*^†

Values are means ± SE. 8-OH-DPAT, 8-hydroxy-2-(di-n-propylamino)-tetralin; CMGs, cystometrograms; VT, volume threshold; CA, contraction amplitude; CD, contraction duration; RV, residual volume; VE, voiding efficiency = VT − RV/VT;

P < 0.05 indicates a statistically significant difference compared with vehicle treatment (post hoc least significance difference test).

^†

P < 0.05 indicates a statistically significant difference compared with 8-OH-DPAT treatment (post hoc least significance difference test).