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. 2009 Dec 30;298(3):F771–F778. doi: 10.1152/ajprenal.00266.2009

Table 6.

Parameters of bladder activity in transurethral CMGs after serial administration of vehicle, 8-OH-DPAT, and WAY-100635 in urethane-anesthetized rats

VT, ml Base, cmH2O CA, cmH2O CD, min ICI, min
Vehicle (n = 12) 0.80 ± 0.29 14.77 ± 1.95 50.94 ± 5.70 0.62 ± 0.15 0.81 ± 0.20
Agonist (8-OH-DPAT; 0.3 mg/kg) 0.33 ± 0.10* 14.99 ± 3.73 58.03 ± 7.56* 0.66 ± 0.23 0.68 ± 0.19
Antagonist (WAY-100635; 0.1 mg/kg) 1.26 ± 0.31* 14.10 ± 2.68 42.86 ± 3.15* 0.65 ± 0.20 1.02 ± 0.16*

Values are means ± SE. Base: basal pressure; ICI: intercontraction interval.

*

P < 0.05 indicates a statistically significant difference compared with vehicle treatment (post hoc least significance difference test).

P < 0.05 indicates a statistically significant difference compared with 8-OH-DPAT treatment (post hoc least significance difference test).