Table 1.
Subject characteristics and initial ventilator settings
| Characteristic/Setting | Value |
|---|---|
| Male gender, % | 60 |
| Age, yr | 52 ± 20 |
| Caucasian, % | 88 |
| Predicted body wt, kg | 66 ± 10 |
| APACHE II on admission, points | 26.6 ± 5.6 |
| Primary physiological injury, % | |
| Pulmonary | 22 |
| Abdominal pathology | 35 |
| Trauma/blood loss | 29 |
| Sepsis | 8 |
| Other | 6 |
| Arterial blood gas analysis at baseline | |
| pH | 7.33 ± 0.09 |
| Arterial Pco2, Torr | 41 ± 8 |
| Arterial Po2, Torr | 98 ± 38 |
| Arterial Po2-to-inspiratory O2 fraction ratio | 146 ± 57 |
| Ventilator settings at baseline | |
| Inspiratory O2 fraction | 0.70 ± 0.18 |
| Vt, ml | 443 ± 102 |
| Vt/predicted body wt, ml/kg | 6.8 ± 1.6 |
| Respiratory rate, min−1 | 24.9 ± 6.2 |
| PEEP, cmH2O | 12.6 ± 4.4 |
| Pplat, cmH2O | 30.5 ± 6.2 |
Values are means ± SD. APACHE II, Acute Physiology and Chronic Health Evaluation II; Vt, tidal volume; PEEP, positive end-expiratory pressure; Pplat, plateau pressure.