Table 1.

Hemodynamic variables of the systemic and pulmonary circulation of the sham, control, and 7-NI groups

	Baseline	3 h	6 h	12 h	18 h	24 h
Mean arterial pressure, mmHg
Sham	108 ± 3	112 ± 4	114 ± 4	112 ± 3	104 ± 2	105 ± 2
B/S Control	93 ± 3	98 ± 5	99 ± 4	99 ± 5	98 ± 6	96 ± 5
7-NI	101 ± 5	112 ± 6	111 ± 5	108 ± 5	102 ± 5	103 ± 7
Sham 7-NI	105 ± 5	105 ± 6	106 ± 3	104 ± 5	104 ± 3	105 ± 5
Mean pulmonary artery pressure, mmHg
Sham	20 ± 0.7	23 ± 0.3	24 ± 0.2	24 ± 0.5	24 ± 0.3	23 ± 0.8
B/S Control	20 ± 0.6	23 ± 0.4	24 ± 0.8	25 ± 0.8	27 ± 1.8	28 ± 2.1†
7-NI	20 ± 0.8	24 ± 1.3	27 ± 0.8	28 ± 1.6	27 ± 1.6	27 ± 1.3
Sham 7-NI	20 ± 1.0	25 ± 1.7	26 ± 1.1	27 ± 1.3	24 ± 2.3	25 ± 1.1
Systemic vascular resistance index (dynes·s·cm−5m2)
Sham	1,279 ± 34	1,173 ± 63	1,287 ± 71	1,376 ± 82	1,320 ± 56	1,294 ± 33
B/S Control	1,100 ± 43	1,380 ± 114	1,241 ± 117	1,290 ± 175	1,134 ± 93	1,203 ± 98
7-NI	1,294 ± 121	1,536 ± 183	1,305 ± 92	1,319 ± 102	1,285 ± 134	1,404 ± 271
Sham 7-NI	1,293 ± 39	1,143 ± 79	1,321 ± 42	1,384 ± 45	1,409 ± 50	1,363 ± 105
Pulmonary vascular resistance index (dynes·s·cm−5m2)
Sham	99 ± 6	94 ± 5	120 ± 3	125 ± 9	139 ± 9	118 ± 7
B/S Control	136 ± 16	140 ± 13	150 ± 16	178 ± 32	180 ± 37	204 ± 39†
7-NI	133 ± 11	157 ± 10	147 ± 7	166 ± 21	171 ± 34	179 ± 37
Sham 7-NI	105 ± 11	128 ± 28	143 ± 14	182 ± 8	149 ± 57	168 ± 39
Cardiac index (l/min/m2)
Sham	6 ± 0.1	7 ± 0.2*‡	7 ± 0.2	6 ± 0.3	6 ± 0.2	6 ± 0.1
B/S Control	6 ± 0.2	5 ± 0.3	6 ± 0.4	6 ± 0.6	7 ± 0.7	6 ± 0.5
7-NI	6 ± 0.4	5 ± 0.4	6 ± 0.4	6 ± 0.5	6 ± 0.6	6 ± 0.8
Sham 7-NI	6.1 ± 0.1	6.8 ± 0.3	5.9 ± 0.1	5.4 ± 0.2	5.3 ± 0.3	5.4 ± 0.2

Data are expressed as means ± SE;

^†P < 0.05 vs. sham;

^*P < 0.05 vs. control;

^‡P < 0.05 vs. 7-NI.