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Oxygenation, expressed as arterial Po2 (mmHg), in rats treated with porcine SP-B surfactant (positive control), lipids (negative control), and the four experimental surfactant preparations with monomeric or dimeric SP-B 1–25 and SP-B 11–25 peptides. The differences between porcine SP-B surfactant and monomeric and dimeric SP-B 1–25 surfactant and the differences between SP-B 1–25 and SP-B 11–25 surfactants or lipids alone are significant (P < 0.001).
