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. Author manuscript; available in PMC: 2010 Mar 15.
Published in final edited form as: Physiol Rev. 2005 Jan;85(1):319–371. doi: 10.1152/physrev.00051.2003

FIG. 21.

FIG. 21

Localization of 6-TM channels in the apical membrane of the proximal tubule. Also shown is the single TM subunit KCNE1 (MinK) that forms the KVLQT1 channel with the 6-TM subunit KCNQ1. These K+ channels are thought to stabilize the apical membrane potential that supports entry of amino acids and glucose via their respective Na+-coupled electrogenic transporters.