FIG. 21.
Localization of 6-TM channels in the apical membrane of the proximal tubule. Also shown is the single TM subunit KCNE1 (MinK) that forms the KVLQT1 channel with the 6-TM subunit KCNQ1. These K+ channels are thought to stabilize the apical membrane potential that supports entry of amino acids and glucose via their respective Na+-coupled electrogenic transporters.
