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. Author manuscript; available in PMC: 2011 Mar 2.
Published in final edited form as: Mol Cancer Ther. 2010 Mar 2;9(3):751–760. doi: 10.1158/1535-7163.MCT-09-0868

Table 4.

Sorafenib pharmacokinetic variables

Day −2 Mean [range] Day 15 Mean [range] P
n 11 6
AUC (μg.h/mL) 70.9 [29.7–149.8] 53.2 [28.3–71.6] 0.89
Cmax (μg/mL) 8.6 [3.1–16.7] 8.6 [4.4–13.8] 0.13
Tmax (h) 4.2 [0–12] 4 [0–12] 0.88