Skip to main content
. 2010 Mar 16;5(3):e9648. doi: 10.1371/journal.pone.0009648

Table 1. Numerical values for memory T cells in mice and humans.

Parameter Values
Human Mouse
Parameter Units IL-15 IL-7 Refs IL-15 IL-7 Refs
Inline graphic Inline graphic 1/102 1/68 [19] 1/17 1/10 [20]
Inline graphic cells Inline graphic Inline graphic [23], [19] Inline graphic Inline graphic [19]
Inline graphic cells/day 0 Inline graphic [16], [19] 0 Inline graphic [19]

The values of Inline graphic for IL-7 are the sum of naive and memory CDInline graphic and naive CDInline graphic T cells. For humans the fraction of cell types in the blood was taken from Vrisekoop [19] and extrapolated to the total body using total cell numbers from Ganusov [23]. For mice, cell numbers in the spleen were taken from Vrisekoop [19] and extrapolated to whole body based on estimates of Inline graphic naive CD8 T cells in the whole body. The Inline graphic value for mice is taken from measurements of specific memory attrition, while for humans it is estimated from thymic output. Because we are interested in attrition rates the indirect measure provides better modeling accuracy.