Table 4. Haplotype distribution of HSPA8 in CHD and control group.
Haplotype * | CHD | Controls | OR (95% CI) | P value | ||
N | % | N | % | |||
AGGT | 850 | 42.37 | 819 | 40.83 | 1.00 | |
GCGT | 495 | 24.68 | 479 | 23.88 | 1.00(0.85, 1.17) | 0.958 |
GCGC | 317 | 15.80 | 392 | 19.54 | 0.78(0.65, 0.93) | 0.006 |
GGAT | 245 | 12.21 | 251 | 12.51 | 0.94(0.77, 1.15) | 0.549 |
GGGT | 38 | 1.89 | 28 | 1.40 | 1.31(0.80, 2.15) | 0.291 |
Others † | 61 | 3.04 | 37 | 1.84 | 1.59(1.04, 2.42) | 0.031 |
Total | 2006 | 100 | 2006 | 100 | -- | -- |
*Polymorphic bases were in 3′ to 5′ order and from left to right the order is rs1461496, rs10892958, rs2276077 and rs2236659.
Other haplotype includes ACGT, GGGC, AGGC, AGAT, GCAT, ACGC, AGAC, GGAC, ACAC, and ACAT with frequency <1.0%.