Table 1.
Contents of Bcl-xl and Bcl-xs mRNA in different types of endometrial tissue and correlation with pathological parameters of the endometrial carcinoma
Classification | Bcl-xl mRNA expression | Bcl-xs mRNA expression | ||
---|---|---|---|---|
χ ± S | P value | χ ± S | P value | |
Normal endometrium | 0.35 ± 4.37 | 0.93 ± 3.05 | ||
Simple hyperplasia | 0.38 ± 3.25 | 0.13 | 0.89 ± 2.00 | 0.12 |
Atypical hyperplasia | 0.37 ± 3.93 | 0.38 | 0.68 ± 0.10 | 0.00 |
Endometrial carcinoma | 0.75 ± 0.13 | 0.00 | 0.49 ± 0.14 | 0.00 |
Degree of Pathological Differentiation | ||||
Well-differentiated | 0.85 ± 7.23 | 0.52 ± 0.14 | ||
Moderately-differentiated | 0.70 ± 7.60 | F = 5.33 | 0.45 ± 0.16 | F = 0.40 |
Poorly-differentiated | 0.70 ± 1.44 | P = 0.02 | 0.48 ± 7.57 | P = 0.68 |
Clinical Staging | ||||
Stage I | 0.74 ± 0.15 | 0.55 ± 7.67 | ||
Stage II | 0.79 ± 0.10 | F = 0.57 | 0.41 ± 2.83 | F = 30.87 |
Stage III | 0.82 ± 0.15 | P = 0.58 | 0.21 ± 7.77 | P = 0.00 |
Lymph Node Metastasis | ||||
No | 0.82 ± 0.16 | F = 2.31 | 0.51 ± 9.16 | F = 0.64 |
Yes | 0.79 ± 0.10 | P = 0.73 | 0.25 ± 6.70 | P = 0.00 |
Depth of Myometrial Invasion | ||||
0 | 0.82 ± 7.26 | 0.58 ± 7.07 | ||
≤ 1/2 | 0.76 ± 0.11 | F = 3.22 | 0.45 ± 0.16 | F = 1.73 |
> 1/2 | 0.64 ± 4.73 | P = 0.07 | 0.45 ± 6.03 | P = 0.22 |