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. 2010 Feb 22;10:22. doi: 10.1186/1471-213X-10-22

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Copyright ©2010 Wang et al; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Morphometric analyses of the skulls of Fgfr2^+/P253Rand Fgfr2^+/S252Wmice. EDMA results from intra-model comparisons between mutant and normal littermates (for further details see Table 1). From top to bottom: superior, lateral and inferior views of micro-CT 3D reconstructions of the skull of a Fgfr2^+/P253Rmouse on the left, and of a Fgfr2^+/S252Wmouse on the right. Red lines indicate linear distances that are significantly shorter in both mutants in comparison with their littermate controls; blue lines represent linear distances that are significantly longer in mutants in comparison to their littermate controls; and green lines show linear distances that are similar in mutants and littermate controls (i.e. no statistical significant differences at the α = 0.1 level).