Table 1.
Patient Baseline Demographic and Clinical Characteristics by Hospital
| Total | Community | University | P | ||
|---|---|---|---|---|---|
| (N = 206) | (N = 127) | (N = 79) | |||
| Age; mean ± stdev | 68 ± 15.8 | 69 ± 15.8 | 66 ± 15.9 | .147 | |
| Sex, male; n, (%) | 111 (54) | 67 (53) | 44 (56) | .681 | |
| Race, Caucasian; n, (%) | 179 (87) | 109 (86) | 70 (89) | .358 | |
| Pre-Stroke mRS; Median (IQR) | 1 (0-2) | 1 (0-2) | 0 (0-1) | .001 | |
| Pre-tx NIHSS;Median (IQR) | 13 (8-17) | 13 (8-17) | 14 (8-17) | .867 | |
| Intracranial Hemorrhage**; n, (%) | 37 (18) | 24 (19) | 13 (16) | .712 | |
| t-PA time*; mean ± stdev | 155 ± 33 | 157 ± 31 | 151 ± 36 | .185 | |
| Baseline stroke risk factors | n, (%) | ||||
| Prior Stroke | 34 (17) | 23 (18) | 11 (14) | .431 | |
| Diabetes | 44 (21) | 28 (22) | 16 (20) | .760 | |
| Hypertension | 142 (69) | 92 (72) | 50 (63) | .168 | |
| High cholesterol | 66 (32) | 41 (32) | 25 (32) | .924 | |
| Hx of coronary artery disease | 65 (32) | 41 (32) | 24 (30) | .775 | |
| Hx of congestive heart failure | 20 (10) | 13 (10) | 7 (9) | .746 | |
| Hx of atrial fibrillation | 58 (28) | 34 (27) | 24 (30) | .576 | |
| Smoking w/in 1 year | 51 (25) | 31 (24) | 20 (25) | .883 | |
*Time, in minutes, from stroke onset to tPA bolus administration.
**Defined as any intracranial hemorrhage at any time point during the index hospitalization.
Abbreviations: mRS = modified estimated Rankin Scale; NIHSS = estimated National Institutes of Health Stroke Scale.