Figure 3.

Superposition of the binding pockets of two structurally different proteins binding ATP. A) overall structures of pdb: PDB: 1E8X in grey and PDB: 1DV2 in red superposed according to their binding sites using Sup-CK. ATP molecules are represented in blue. B) Superposition of the ATP molecules from PDB: 1DV2 and PDB: 1E8X when their binding sites are superposed. C) Positively charged protein regions around ATP molecules of PDB: 1E8X in grey and PDB: 1DV2 in red. D) Protein hydrophobic patches around ATP molecules of PDB: 1E8X in grey and PDB: 1DV2 in red.