Figure 4.
Doxorubicin induced ovarian apoptosis. Confocal micrographs of ovaries excised from doxorubicin or saline-injected mice, 12 or 24 hours after treatment. Ovaries of saline-treated mice (A, A'A"). Ovaries of doxorubicin-treated mice 12 hours (B, B'B") or 24 hours (C, C'C") after treatment. Magnification: ×10 (A-C), ×20 (A'-C'), ×63 (A"-C"). (A) TUNNEL staining (green), (B) caspase-3 staining (red). Blue staining represents DNA labeling by Heochst 32242.