Table 1.
Cell line | Number of grafted CAMs | Embryos died | Number of - tumours | Number of + tumours | Ratio +/- |
% dead | P-value* |
---|---|---|---|---|---|---|---|
MNNG-HOS | 23 | 6 | 6 | 11 | 11/17 | 26.1 | NS |
U2OS | 21 | 11 | 5 | 5 | 5/10 | 52.4 | 0.0294 |
SAOS | 20 | 14 | 3 | 3 | 3/6 | 70 | 0.0008 |
OST | 8 | 2 | 5 | 1 | 1/6 | 25 | NS |
MG63 | 14 | 7 | 4 | 1 | 1/7 | 50 | NS |
HOS | 20 | 5 | 13 | 2 | 2/15 | 25 | NS |
ZK58 | 35 | 11 | 21 | 3 | 3/24 | 31.4 | NS |
SJ-SA-1 | 11 | 2 | 9 | 0 | 0/9 | 18.2 | NS |
Controls | 26 | 5 | 19.2 |
n = number, - = no tumour/tumour ≤ 2 mm, + = vascularized tumour > 2 mm
*Fisher's exact test (cell line vs. controls); NS = not significant