Table 6.
No relapse prior to tx |
Relapsed prior to tx |
||||
---|---|---|---|---|---|
Outcome of interest | N (eval) | Probability (95% CI) | N(eval) | Probability (95% CI) | P-valuec |
Treatment related mortalitya | 38 | 21 | |||
@ 1 year | 5 (1–15)% | -- | N/A | ||
@ 3 years | 5 (1–15)% | -- | N/A | ||
@ 5 years | 5 (1–15)% | -- | N/A | ||
Progression/relapsea | 38 | 21 | |||
@ 1 year | 54 (38–70) % | 74 (52–90)% | 0.135 | ||
@ 3 years | 63 (47–77) % | 74 (52–90)% | 0.400 | ||
@ 5 years | 63 (47–77) % | 74 (52–90)% | 0.400 | ||
Progression free survivalb | 38 | 21 | |||
@ 1 year | 41 (26–57) % | 26 (10–48) % | 0.275 | ||
@ 3 years | 32 (18–48) % | 26 (10–48) % | 0.664 | ||
@ 5 years | 32 (18–48) % | 26 (10–48) % | 0.664 | ||
Overall survivalb | 38 | 21 | |||
@ 1 year | 53 (37–68) % | 62 (41–81) % | 0.487 | ||
@ 3 years | 39 (25–55) % | 43 (23–64) % | 0.800 | ||
@ 5 years | 36 (22–52) % | 29 (12–49) % | 0.532 |
Probabilities of relapse, treatment-related mortality, platelet & neutrophil engraftment were calculated using the cumulative incidence function
Probabilities of overall survival and progression free survival were calculated using the Kaplan-Meier product limit estimate.
Pointwise P-value