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. Author manuscript; available in PMC: 2011 Mar 12.
Published in final edited form as: Biochem Biophys Res Commun. 2010 Feb 10;393(3):471–475. doi: 10.1016/j.bbrc.2010.02.025

Fig. 4.

Fig. 4

Inhibition of DMT1-mediated Fe2+ transport by the alkaline-earth metals. We measured uptake of 2 μM 55Fe2+ at pH 5.5 in standard transport medium (None) or in the presence of 20 mM Ca2+, Ba2+, Mg2+, or Sr2+ in control oocytes and oocytes expressing DMT1 (n = 12-16). Two-way ANOVA revealed an interaction (P < 0.001); a within DMT1, all treatments with alkaline-earth metals differed from no treatment (P < 0.001).