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Increased cell death in aging-related and surgical OA in mouse joints. A–C, Knee joints from 2, 9, 12 month old C57Bl/6J mice were used to evaluate PARP p85 expression by immunohistochemistry (IHC). Knee joints from C57BL/6JWT mice aged 2 months (n=3), 9 months (n=3) and 12 months (n=3) were examined. D–E, Knee joints from 2 months old C57Bl/6J mice with sham surgery (n=3) and surgical OA at 8 weeks (n=3) were evaluated for PARP p85 expression by IHC. Magnification: x40.
