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. Author manuscript; available in PMC: 2010 Apr 1.
Published in final edited form as: Pharmacol Ther. 2010 Feb 1;126(1):56–68. doi: 10.1016/j.pharmthera.2010.01.002

Figure 1. Spinal nerve ligation (SNL) induces a substantial upregulation of CX3CR1 in spinal cord microglial cells.

Figure 1

(a) Upregulation of CX3CR1 in the ipsilateral side of the spinal cord (L5), 3 days after ligation of the L5 spinal nerve. (b–d) Double staining reveals a complete co-localization of CX3CR1 with the microglial marker OX-42 in the dorsal horn. Scales, 100 μm. The images are re-produced from a paper by Zhuang et al., 2007 (Brain, Behavior, and Immunity) with permission.