Skip to main content
. Author manuscript; available in PMC: 2010 Apr 1.
Published in final edited form as: Pharmacol Ther. 2010 Feb 1;126(1):56–68. doi: 10.1016/j.pharmthera.2010.01.002

Figure 3. Spinal nerve ligation (SNL) induces upregulation of CCL2 in spinal cord astrocytes.

Figure 3

(a, b) Upregulation of CCL2 in the ipsilateral side of the spinal cord, 3 days after ligation of the spinal nerve. (c) Double staining reveals a co-localization of CCL2 (red) with astrocyte marker GFAP (green) in the superficial dorsal horn. (d) Double staining of CCR2 (green) with neuronal marker NeuN (red) in the dorsal horn of naïve animals. Spinal cords were obtained from CCR2-GFP mice. Scales, 50 μm. The images are re-produced from a paper by Gao et al., 2009 (J Neurosci) with permission.