Table II.
Response of epidemic Kaposi sarcoma in children to chemotherapy and antiretroviral drug combinations
| Responsea, n |
||||
|---|---|---|---|---|
| Therapyb | Complete | Partial | None | Unknown |
| VCR | - | 4 | - | 1 |
| BV | 1 | 1 | - | 3 |
| ART | 2 | - | - | 13 |
| VCR + ART | 4 | 2 | - | 2 |
| BV + ART | 13 | 4 | 1 | - |
| None | - | - | - | 22 |
|
| ||||
| Total | 20 | 11 | 1 | 41 |
a
Complete response defined as no evidence of residual KS; partial response defined as any appreciable reduction in the size or number of KS lesions; no response defined as the lack of partial response or progression of KS.
b
VCR = vincristine; BV = bleomycin plus vincristine; ART = antiretroviral therapy, made up of 2 nucleoside reverse transcriptase inhibitors plus either a protease inhibitor (15 patients received ritonavir-boosted lopinavir) or a non-nucleoside reverse transcriptase inhibitor (16 patients received efavirenz and the other 10 received nevirapine).