Figure 6. Attenuation of foot process effacement and podocyte loss in the glomeruli of gp91phox KO mice.
A. gp91phox gene deletion improved podocyte ultrastructure in FF diet-treated mice. Arrow denotes the area of foot process effacement in WT mice on the FF diet. Images are representative of 6 TEM images per kidney from 3 mice per group. Original magnification: ×8,000. B. Typical images of WT1-stained glomeruli from 4 groups of mice (Original magnification, ×400). C. Summarized data showing podocyte numbers per glomerulus in each group (n=6). * p<0.05 vs. WT mice on the normal diet; # p<0.05 vs. WT mice on the FF diet.