Table 4.
Drug use, depression, and calcium and vitamin D intake of 5879 men aged 65 and over with and without incident rib fracture (MrOS Study). Values are numbers (percentages) unless stated otherwise
| Characteristics | No incident rib fracture (n=5753) | Incident rib fracture (n=126) | P value* |
|---|---|---|---|
| Drug use: | |||
| Loop diuretic | 277 (4.8) | 5 (4) | 0.8 |
| SSRI | 150 (2.6) | 6 (5) | 0.1 |
| Tricyclic antidepressant | 93 (1.6) | 4 (3) | 0.1 |
| Thyroid hormone | 375 (6.5) | 12 (10) | 0.2 |
| α blocker | 866 (15.1) | 26 (21) | 0.08 |
| Androgen | 25 (0.4) | 0 (0) | >0.99 |
| ACE inhibitor | 1036 (18.0) | 22 (17) | 0.9 |
| Benzodiazepine | 164 (2.9) | 6 (5) | 0.2 |
| β blocker | 1013 (17.6) | 20 (16) | 0.6 |
| Statins | 1482 (25.8) | 40 (32) | 0.1 |
| Nitrates | 217 (3.8) | 6 (5) | 0.6 |
| Depressed mood most or all of the time | 171 (3.0) | 5 (4) | 0.5 |
| Mean (SD) calcium intake (mg) | 735 (465) | 708 (391) | 0.3 |
| Mean (SD) vitamin D intake (IU) | 431 (409) | 402 (424) | 0.4 |
ACE=angiotensin converting enzyme; SSRI=selective serotonin reuptake inhibitor.
*For differences in rib fracture case status by χ2 or Fisher’s exact test for categorical variables, two sided t tests for normally distributed continuous variables, and Wilcoxon rank-sum test for skewed continuous variables.