TABLE 6.
Standardized incidence ratio of primary lung cancer in 4,502 Danish males with nonsyndromic oral cleft during follow-up from 1943 through 1998*
| Primary lung cancer† |
Observed (no.) |
Expected (no.) |
Standardized Incidence ratio |
95% Confidence interval |
|---|---|---|---|---|
| Cleft lip only | 1 | 1.98 | 0.51 | 0.01, 2.82 |
| Cleft lip + cleft palate |
7 | 2.81 | 2.49‡ | 1.00, 5.14 |
| Cleft palate only | 2 | 0.96 | 2.09 | 0.23, 7.53 |
*
Data are stratified into subtypes of nonsyndromic oral cleft.
†
None of the syndromic cleft cases had primary lung cancer or cancer of the trachea.
‡
Statistically significant standardized incidence ratio.