Figure 4.
Logarithmic presentation of quantitative expression analysis of angiogenic factors and corresponding receptors from microdissected endothelial cells of MT/ret melanoma. Laser microdissected intratumoral endothelial cells from cryosections of high and low angiogenic-active MT/ret melanoma were used for the quantitative real-time PCR analysis of angiogenic factors and their corresponding receptors (n = 5 high and 4 low angiogenic tumors of three mice). Total RNA of bEND3 cells and mouse brain and heart was used as a control for angiogenic factor expression. The analyses for each factor were done in triplicate for each experiment. Three independently performed experiments showed corresponding outcomes. Error bars, mean ± SD.
