Figure 1.
1α,25(OH)2D3-induced IL-10 production by BMCMCs. (A) FACS analysis of WT (B6) BMCMCs and VDR−/− BMCMCs for VDR expression. (B) IL-10 in supernatants of 5-wk-old (B6J) BMCMCs cultured for 24 h with 0.1–1,000 nM 1α,25(OH)2D3. Data (n = 5 per group) are of mean values obtained in five different experiments (all measurements for each experiment were performed in duplicate). *, P < 0.05 or **, P < 0.01 for the indicated comparisons. See Fig. S1 B for data using VDR−/− BMCMCs.