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. 2009 Oct 20;18(1):198–205. doi: 10.1038/mt.2009.248

Figure 2.

Figure 2

Expression of dystrophin restores the dystrophin-associated protein complex (DAPC) to the sarcolemma in the PPMO-treated dKO mice. DAPC components α- and β-sarcoglycan, β-dystroglycan, and nNOS were detected by immunostaining in tissue cross-section of tibialis anterior (TA) muscles from PPMO-treated dKO mice (right panel), compared with C57BL6 normal mice (left panel) and untreated dKO mice (middle panel). Bar = 100 µm. dKO, double-knockout; nNOS, neuronal nitric oxide synthase; PPMO, peptide-conjugated phosphorodiamidate morpholino oligomer.