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. 2009 Dec 29;18(3):617–624. doi: 10.1038/mt.2009.294

Figure 1.

Figure 1

Immunity to rAAV6, rAAV1-E531K, and rAAV1 at week 4 following intramuscular injection. rAAV6-cFIX: panels a1, b1, c1, and d1; rAAV1-cFIX: panels a2, b2, c2, and d2; rAAV1-E531K: panels a3, b3, c3, and d3; buffer control: panels a4, b4, c4, and d4. Panels a1–a4, immunofluorescence staining with anti-cFIX antibody (green); b1–b4, H&E staining; c1–c4, immunofluorescence with anti-CD8 (green) and DAPI-stained nuclei (blue); d1–d4, immunofluorescence with anti-CD4 (green) and DAPI-stained nuclei (blue). cFIX, canine factor IX.