Figure 3. Selectin-specific PLNP binding to endothelium in the lungs following LPS treatment.

WT C57/BL6 (A) or E/P−/− (B) mice received selectin PLNP intravenously 2 h after LPS administration, and lung tissues were collected 3 h later. The pattern of binding of fluorescent PLNP was examined by fluorescence microscopy (×400). Data is representative of three independent experiments. PLNP, nanoparticles; e, endothelium; bv, blood vessel; L, leukocyte.