Figure 5. Attenuation of cockroach allergen-induced AHR by selectin PLNP.
Negative control PLNP or selectin-specific PLNP were administered i.v. to Balb/c mice, 2 h after the final intratracheal CRA challenge (day 20). The level of airway resistance was determined following methacholine challenge, and the effect of administration of selectin PLNP or control PLNP compared with mice receiving CRA alone. Data is representative of three independent experiments and expressed as mean ±SE (n=5–6 mice per group).