Fig. 3.
Performance of each experiment in rediscovering the 273 gold standard positives (columns). Each row is a single experiment, sorted by positive predictive value, with highest at the top. Left-most column indicates the experiment number (Supplementary Table 1). Left grid (green) indicates species, middle (red) measurement type, and right (blue) control or obesity-related. Abbreviations: H, Human; M, Mouse; R, Rat; W, Worm; G, Genetics; M, Microarray; P, Proteomics; R, RNAi; K, Knowledge; C, Control. Microarray experiments are shown at both 5% (red) and 10% (pink) false-discovery rates. White elements are genes unmeasured in an experiment. In each row, darkest elements are gold standard genes positive in an experiment, lighter elements are gold standard genes measured in an experiment, but not positive. Four control experiments have a blue border. Bar chart at extreme right visually indicates total number of positives identified in each experiment, ranging from 0 to 3067. All 273 genes were measured in at least one experiment, but 89 genes are not positive in any experiment.