Figure 2.

δ-SG as a candidate causative gene common to both HCM and DCM hamsters. (a) Western blot analyses of α- and δ-SGs and α- and β-DGs for LVs. CBB; Coomassie staining. Note that reduction of α-DG was more prominent than that of β-DG in all the CM hamsters. (b) RNA blot analyses of α-, β-, γ-, and δ-SGs. The transcript sizes are 1.5 kb for α-, 4.5 and 3.0 kb for β-, 1.7 kb for γ-, and 9.5 kb for δ-SGs. Besides the 9.5-kb transcript, there were also 4.3-, 2.3-, and 1.4-kb δ-SG transcripts, none of which was detectable in any CM hamsters. Full-length cDNAs for Golden hamster α-, β-, γ-, and δ-SGs were used as probes. BF, biceps femoris.