Table 1.

Effects of daintain/AIF1 on the insulin and glucose elimination rates

	AUC, nmol/liter in 20 min	KG, % per min	n
Experiment series 1
Glucose alone	10.2  ±  1.7	2.4  ±  0.1	17
Glucose + peptide,	17.2  ±  2.4*	2.7  ±  0.1*	15
75 nmol/kg
Experiment series 2
Glucose alone	9.2  ±  0.6	2.2  ±  0.1	17
Glucose + peptide,	15.7  ±  3.0*	2.6  ±  0.1*	17
7.5 nmol/kg
Experiment series 3
Glucose alone	11.4  ±  1.7	2.4  ±  0.2	12
Glucose + peptide,	13.2  ±  2.1	2.3  ±  0.1	12
750 pmol/kg
Experiment series 4
Glucose alone	10.1  ±  1.2	2.7  ±  0.1	12
Glucose + peptide,	6.2  ±  1.1*	2.1  ±  0.1†	12
75 pmol/kg

The area under the curve for insulin (AUC) and the glucose elimination rate (K_G) during 20 min after the intravenous injection of glucose (1 g/kg) with or without addition of daintain/AIF1 at four different dose levels in anesthetized NMRI mice is shown. Means ± SEM are given. n indicates number of animals, ∗ indicates P < 0.05, and  

^† indicates P < 0.01 between the groups.