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Effects of D1R agonist and antagonist treatments on locomotor activity. Locomotor activities were measured in the OF paradigm for 30 min before injection and for another 60 min after injection of SKF 81297 (A and B) or SCH23390 (C and D). Graphs show the mean values ± SEM (10 min bins). ANOVA Fisher’s PLSD test, n = 10 each genotype in the SKF 81297 experiment, n = 7 each genotype in the SCH23390 experiment; #, P < 0.05 (treatment effect for a given genotype).
