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. Author manuscript; available in PMC: 2011 Apr 28.
Published in final edited form as: Neuroscience. 2010 Jan 20;167(1):68–87. doi: 10.1016/j.neuroscience.2010.01.022

Table 1.

Width of labeled region of extrasynaptic NMDARs using immunogold localization of NR1 in CA1 stratum radiatum of hippocampus, or DAB/immunoperoxidase of hippocampal neuronal cultures

Experiment* Average in nm (N=) Range in nm Combined averages
Gold particles 25 (77) 5-93
Flag-NR2A-in vitro 227 (35) 50-560
Myc-NR2B-in vitro 251 (65) 51-768 Transf. 2A+2B=243#
NR2A-in vitro 198 (50) 51-538
NR2B-in vitro 186 (69) 51-602 Native 2A+2B=191#
*

Gold particle clusters of 2-6 5 nm gold particles were counted from 13 experimental groups on 2 animals. Live surface NR2A or NR2B labeling was counted from 2 experiments.

#

p=0.00127 for transfected NR2 subunits versus native NR2 subunits.

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