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. 2010 Jan 8;114(2):310–322. doi: 10.1093/toxsci/kfq002

FIG. 2.

FIG. 2.

Mn levels in plasma and striatum of saline-exposed (control) and manganese-exposed (Mn) animals. (A) GFAAS was used to determine the amount of Mn in plasma from rats at the last week of study (6 weeks). Mn content was statistically significantly increased (p < 0.05) in plasma of rats exposed to Mn compared to saline-injected animals. (B) GFAAS was used to determine the amount of Mn in striatal brain tissue samples obtained from rats at the last week of study (6 weeks). Values are expressed as percent change from control (mean ± SEM for Mn levels in striatum of saline-exposed rats is 350.30 ± 139.10 nmol/g tissue). Twofold increases in Mn content was seen in striatum of rats exposed to Mn compared to saline-injected animals, but the difference was not statistically different.