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The postulated mechanism of action of catumaxomab: The intact trifunctional antibody catumaxomab accelerates the recognition and destruction of tumor cells by different immune cells. ADCC, antibody-dependent cellular toxicity; DC-CK1, dendritic cell cytokine 1; iL, interleukin; IFNγ, interferon gamma; TnFα, tumor necrosis factor alpha; LFA, lymphocyte function antigen; nK, natural killer; GM-CSF, granulocyte monocyte colony stimulating factor.
