. 2010 Mar-Apr;2(2):181–189. doi: 10.4161/mabs.2.2.11158

Table 2.

Summary of fold improvements for multiple cellular and non-cellular effector arms

	CDC		ADCC		ADCP
ID^a	Potency^b	Efficacy^c	Potency^b	Efficacy^c	Potency^b	Efficacy^c
FT	3.3	1.1	1.2	1.2	1.2	1.2
EFT	6.9	1.1	0.045	0.68	0.91	0.94
FT + DE	3.3	1.1	22	3.4	3.7	1.2
FT + AE	3.2	1.1	5.3	2.1	4.7	1.2
EFT + AE	23	1.1	1.2	1.0	0.46	1.0
DE	1.0	0.94	22	3.3	5.4	1.2
AE	1.2	1.0	8.3	2.5	2.5	1.3

^aVariant ID’s as in Table 1, plus: DE (S239D/I332E) and AE (G236A/I332E). ^bPotency Fold = EC₅₀ (Native IgG1)/EC₅₀ (variant). ^cEfficacy Fold = Maximum Lysis (variant)/Maximum Lysis (Native IgG1).