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Secretion of inflammatory cytokine production by Muc1+/+ and Muc1−/− primary lung DC (see Materials and Methods; ad). Data are described as pg of cytokine secreted per million DC (pg/106 cells) ± 1 standard deviation about the mean (n = 3 independent experiments of 6 mice per group). The following cytokines were quantified: IL-12p40 (a), TNF-α (b), IL-10 (c), KC production (d). ∗ p < 0.05; ∗∗ p < 0.01; + p < 0.05, all wild-type vs. knockout DC. FLA = Flagellin stimulated.
