Fig. 1.

miR-19a is rapidly induced by shear stress in ECs. (A) Scatter plot of miR expression profiles in ECs in response to laminar shear stress (12 dyn/cm² for 12 h, y axis) and control ECs kept under static condition (x axis). The miRs differentially expressed with statistical significance are marked in red. (B) qRT-PCR shows that miR-19a was induced in ECs after being exposed to laminar shear stress for various time durations. U6 snRNA level was used for normalization. Data are presented as the mean ± SEM (n = 3). *P < 0.05 compared with static control).