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. Author manuscript; available in PMC: 2010 Jul 1.
Published in final edited form as: Pediatrics. 2009 Jul;124(1):241–250. doi: 10.1542/peds.2008-2281

TABLE 5.

APOE Genotype Effects

Outcome P ε2 ε4


B SE B SE
Head circumference at 4 y .0361 −0.7129 0.2815 −0.0092 0.1989
Full-scale IQ .4686 0.3198 2.7477 2.3476 1.9213
PLS-4 TLS .2201 −2.3985 2.6563 2.3367 1.8785
Attention/impulsivity (ADHD Rating Scale-IV)
    Inattentive .2998 0.9084 0.8851 −0.5746 0.6269
    Hyperactivity/impulsivity .1835 −1.0109 0.9095 −1.0852 0.6452
Behavior (CBCL/1.5–5)
    Emotionally reactive .3778 −0.2497 1.0552 −1.0872 0.7481
    Anxious/depressed .0703 0.0891 0.9281 −1.4666 0.6573
    Somatic complaints .0091 1.5501 1.1750 −2.0052 0.8293
    Withdrawn .1813 1.6568 1.2038 −0.7818 0.8518
    Sleep problems .0698 −2.1188 1.1512 −1.2346 0.8144
    Attention problems .1980 1.5528 1.0980 −0.6092 0.7773
    Aggressive behavior .2354 −1.3357 1.1006 −0.9227 0.7771
    Affective problems .4650 0.0265 1.1821 −1.0081 0.8387
    Anxiety problems .2014 −0.1839 1.1435 −1.5321 0.8098
    PDPs .0324 2.4156 1.2733 −1.2316 0.8981
    ADHD problems .4736 −0.5374 0.8807 −0.7287 0.6235
    Oppositional-defiant problems .3664 −1.1151 0.9909 −0.3706 0.6974
    Internalizing problems .0093 1.4324 1.8801 −3.9978 1.3234
    Externalizing problems .5494 0.5396 1.8454 −1.2605 1.3051
    Total problems .0807 1.0139 1.8624 −2.6556 1.3149
Social skills (PKBSs)
    Social skills total score .0087 −4.3912 2.1242 2.7860 1.5174
    Externalizing problems proportion .2238 2.0399 4.2638 −4.5846 3.0235
    Internalizing problems proportion .1621 1.9621 4.7187 −4.7305 3.3973
    Problem behavior total score .2392 0.8414 2.2370 −2.4271 1.5829
Attention/executive function (NEPSY)
    Visual attention .9603 −0.0783 0.4501 0.0568 0.3169
    Statue .0016 0.6175 0.6254 1.5700 0.4345