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Ses1 colocalizes with OCRL on endocytic structures. (A) Spinning disk confocal image showing a section of a Cos7 cell expressing TagRFP-T-Ses1 and GFP-OCRL. (Scale bar, 5 μm.) (B) TagRFP-T-Ses1 and GFP-OCRL also colocalize on macropinosomes. (Scale bar, 4 μm.) (C) TagRFP-T-Ses1–positive macropinosomes are positive for GFP-EEA1 and GFP-WDFY2, two markers of PI3P-positive, Rab5-positive endosomes (35, 41). (Scale bar, 2 μm.)
