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Design of PAs for articular cartilage regeneration. Chemical structure of (A) TGF-binding PA and (B) nonbioactive filler PA. (C) Illustration of coassembly of the TGF-binding PA and the filler PA showing binding epitopes exposed on the surface of the nanofiber. (D) ELISA results showing TGFβ-1 release up to 72 hours from filler PA and 10 mol% TGF-binding PA (TGFBPA). 100 ng/mL of TGFβ-1 were loaded in all gels. Error bars equal standard deviation, n = 4.
