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. 2010 Feb 3;107(8):3734–3739. doi: 10.1073/pnas.0911377107

Fig. 5.

Fig. 5.

LXR ligand GW3965 dose dependently inhibits IL-1β–induced PGE2 production (A) and COX-2 expression (B) in SW982 cells. (A) A dose curve generated to show potent inhibition of PGE2 production by GW3965 treament. (B) Relative expression levels of COX-2 evaluated by real-time PCR, using GAPDH as endogenous control. *P < 0.05 versus IL-1β–treated group.