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. 2010 Feb 4;107(8):3740–3745. doi: 10.1073/pnas.0911542107

Fig. 2.

Fig. 2.

Nerve blockade with 25 mM QX-314 and OTAB. (A) Duration of block from 25 mM QX-314 with increasing concentrations of OTAB. Sample size (n): 10 mM, 6; 20 mM, 20; 30 mM, 10; 40 mM, 4; 120 mM, 4. Asterisks refer to comparison of duration of sensory and motor block. (B) Percent suppression of thermal nociception and motor function over time from 25 mM QX-314 + 20 mM OTAB. n = 19. (C) Effect of increasing the QX-314 concentration beyond 25 mM with 30 mM OTAB. Sample size (n): 5 mM, 4; 25 mM, 10; 45 mM, 4; 70 mM, 4; 100 mM, 4. Data are medians with 25th and 75th percentiles. *P < 0.05; **P < 0.01; ***P < 0.001, comparison of sensory and motor block. †See Fig. 1.