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IC50 values and sequence identity using chitinases from different species.
| Enzyme |
IC50 (μM) (Closantel) |
IC50 (μM) (Allosamidin) |
% Identity |
| OvCHT1 | 1.6 ± 0.08 | 0.0013 ± 0.0003 | 100 |
| BmCHT1 | 9.0 ± 0.35 | 0.0018 ± 0.00004 | 67 |
| EhCHT1 | 78 ± 34 | 0.122 ± 0.0037 | 13 |
| PfCHT1 | 132 ± 32 | 0.0254 ± 0.0004 | 13 |
| HsCHT1 | n.d. | 0.0119 ± 0.0007 | 35 |
n.d. = not determined
