Table 5.
effects of various natural agents and their combination with VC on PC-3 cells
| Natural agents | Cell growth/viability (%) |
|
|---|---|---|
| No additions | +VC (200 μM) | |
| ABE | 100% | 100% |
| HMM | 100 | 100 |
| STMa | ~80 | ~50 |
| RGMa | ~47 | ~10 |
| ASC | 100 | 100 |
| MSK | 100 | 100 |
| AHC | 100 | 100 |
| ARBX | 100 | 100 |
| YBGb | <5 | N/A |
| 100 | ~10 | |
Notes:
Five hundred μg/ml each of STM and RGM was used solely while 150 μg/ml each of these agents (in comparison with PDF) was used for VC (200 μM) combination study, but this VC alone had no effects. For the rest of agents (excluding YBG), a maximum concentration of 1,000 μg/ml was tested solely and in combination with VC;
Concentration of YBG used here was 20 μg/ml based on the amount of β-glucan, but it also contained the estimated, lethal dose of 2,400 μM VC. Accordingly, YBG has been dismissed from this study and see the text for further explanation.
Abbreviations: ABE, Agaricus blazei Murill mushroom extract; HMM, Himematsutake (Iwade Strain 101) extract; STM, Shiitake (Lentinus edodes) mushroom extract; RGM, Reishi (Ganoderma lucidum) mushroom extract; ASC, Mixed powder of Agaricuc blazei Murill and shark cartilage; MSK, Mixed powder of 3 different mushrooms and 3 herbs; AHC, Mycelial extracts of several mushrooms; ARBX, Arabinoxylan from rice bran; YBG, Yeast cell wall extract; N/A, not applicable.