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. 2010 Feb 17;30(7):2676–2685. doi: 10.1523/JNEUROSCI.4022-09.2010

Figure 4.

Figure 4.

Effect of altering NR2A expression on LTP. A, Histograms showing the average ratio of the NMDA–EPSC (n = 21, 6, and 6) (a), the ratio of the half-width (HW) (n = 21, 6, and 6) (b), and the ratio of the AMPA–EPSC in transfected cells to that of untransfected cells (n = 13, 13, and 10) (c), respectively, for NR2A–RNAi, NRB RNAi plus NR2A, or NR2A. B–D, Time course of LTP for untransfected cells (open circles) and neighboring cells transfected with NR2A–RNAi (n = 11; p = 0.2) (B), NR2A plus NR2B–RNAi (n = 8; p < 0.007) (C), and NR2A (n = 7; p < 0.05) (D) (Wilcoxon's test at 20–30 min). Insets show example averaged EPSCs taken before and 30 min after pairing. *p < 0.05.