Table 3.
Differences in QOL and clinical characteristics between baseline and 1-year for patients treated with chemoradiation alone and those requiring neck dissection.a
| Measure | Chemoradiation alone N=65 |
+ Neck dissection N=38 |
||||
|---|---|---|---|---|---|---|
| Baseline | 1-Year | Change | Baseline | 1-Year | Change | |
| SF36 | ||||||
| Physical Functioning |
76.5 (26.6) | 68.2 (25.8) | −8.3* | 79.4 (22.2) | 71.1 (23.1) | −8.2* |
| Role Physical | 57.7 (42.6) | 46.5 (44.3) | −10.9 | 53.3 (41.6) | 44.7 (43.6) | −8.6 |
| Body Pain | 64.2 (26.5) | 72.2 (21.6) | 8.0** | 62.4 (23.3) | 60.2 (25.1) | −2.2 |
| General Health Perceptions |
63.4 (19.8) | 63.4 (20.8) | −0.4 | 61.1 (19.4) | 62.6 (20.9) | 1.6 |
| Vitality | 51.5 (24.2) | 53.3 (20.4) | 1.8 | 51.7 (21.7) | 52.9 (22.2) | 1.2 |
| Social Functioning | 70.0 (26.2) | 72.5 (25.3) | 2.5 | 66.4 (29.7) | 74.7 (25.1) | 8.2 |
| Role Emotional | 63.6 (44.0) | 70.3 (39.0) | 6.3 | 58.8 (43.5) | 66.7 (40.3) | 7.9 |
| Mental Heath | 68.5 (19.1) | 74.7 (18.5) | 6.2* | 62.7 (20.0) | 70.5 (20.6) | 7.8* |
| HNQOL | ||||||
| Eating | 76.6 (25.7) | 55.7 (22.2) | −20.9** | 81.8 (21.3) | 57.0 (24.1) | −24.8** |
| Communication | 76.0 (24.1) | 70.8 (27.3) | −5.2 | 75.8 (22.6) | 69.2 (24.7) | −6.6 |
| Emotional Distress | 68.2 (19.1) | 79.2 (18.5) | 11.0** | 61.8 (22.5) | 72.9 (23.2) | 11.1** |
| Pain | 66.6 (26.2) | 71.3 (21.7) | 4.7 | 59.7 (21.2) | 63.0 (27.1) | 3.3 |
| Clinical Characteristics | ||||||
| Mean BMI | 27.2 (5.3) | 23.5 (3.7) | −3.7** | 29.4 (6.7) | 24.9 (5.1) | −5.5** |
| Disabled | 19 (46%) | 14 (37%) | 6 (23%) | 12 (44%) | ||
| Depressive Symptoms |
30 (46%) | 20 (32%) | ** | 21 (55%) | 15 (41%) | ** |
| Smoker, past month | 22 (34%) | 11 (17%) | ** | 13 (34%) | 4 (11%) | ** |
| Alcohol Problem | 10 (16%) | 2 (3%) | * | 9 (24%) | 2 (5%) | |
a
Tested for differences in the same group from baseline to 1-Year using paired t-tests for continuous variables and the Sign test for dichotomous variables. Differences between groups are presented in Table 4.
*
p<.05
**
p < .01